Unexplained Infertility

 

“Follicular fluid from one female was better at attracting sperm from one male, while follicular fluid from another female was better at attracting sperm from a different male,” said Professor Fitzpatrick. This shows that interactions between human eggs and sperm depend on the specific identity of the women and men involved.”

The egg does not always agree with the woman’s choice of partner. The researchers found that eggs did not always attract more sperm from their partner than from another male.

Is this egg or sperm choice? Professor Fitzpatrick explained that sperm have only one job – to fertilise eggs – so it doesn’t make sense for them to be choosy. Eggs, on the other hand, can benefit by picking high-quality or genetically compatible sperm.

“The idea that eggs are choosing sperm is really novel in human fertility,” said Professor Daniel Brison, “Research on the way eggs and sperm interact will advance fertility treatments and may eventually help us understand some of the currently ‘unexplained’ causes of infertility in couples.