Friday, December 24, 2021
The Hyksos (Hebrews) of Avaris (Tel Yehudiya)
One has only to look at Ancient Egyptian monuments to understand how monstrous a people they were. Leons with human faces, humans with jackal faces, enormous pyramidal tombs for mummified cats, etc. Their religion was an absurd mix of crocodile gods, and so. Their king married their sisters, ensuring their progressive mental and physical decline. Their myths were pornographic like Kamutef, the sun god who every night inseminated Nut, the goddess of heaven. Every morning, she gave birth to him again in a process of daily renewal. Nut is therefore both the mother and wife of the sun. In royal mythology, the pharaoh hoped to achieve renewal in a similar way to the myth, in which mother and wife were conceptualized identically. The only sensible kings were the Hyksos, immigrant Hebrew pastoralists, who believed in one god and built no grandiose tombs. The natives were absolutely humiliated by being dominated by this small foreign, light-skinned tribe and after 150 years they expelled the Hyksos to their original country in Israel.
Is the new Chinese generation lactase tolerant?
How the market overcomes the obstacle of lactose intolerance in China?
It is true that Asian people are genetically predisposed to lactase-deficiency (around 85% of people suffer from lactose intolerance in China). Older generations of Chinese who were not used to consuming dairy products in their diets are also mostly lactose intolerant.
But this lactose intolerance in China will not slow down the market. First, because to create new generations of milk drinkers, society and government have taken several measures. Today Chinese babies are born with the ability to make lactase, which is the enzyme needed to digest the milk vector and which is lost as they grow older. Moreover, children do not stop drinking milk as they grow up and therefore continue to produce this enzyme. Source: A market research consulting
The Israeli model farm near Beijing created this market in China. I was skeptical but Dr Moshe Mizrahi was right - the Chinese will learn to drink milk. Curiously, the architecture of the ad looks Mediterrranean, Greek maybe.
Wednesday, December 22, 2021
Lu Xun, The True Story of Ah-Q
Study the revolutionary spirit of Lu Xun, become a pathbreaker in the criticism of Lin Biao and Confucius, 1974
I am reading the complete works of Lu Yun, a radical Chinese writer of the 1920s who became the hero of the Cultural Revolution. His story The Diary of a Madman is rather impressive. The Chinese imperial society was really very bad, but the Maoist was not a paradise. I think they are regaining the balance now.
Tuesday, December 21, 2021
Nothing works
Mussolini's Battle for Births was a failure. Marriage rates stayed virtually the same during Mussolini's reign, and birth rates decreased until 1936, after which there was a modest increase. The birth rate of 112 per 1000 in 1936 was below that of pre-World War I levels (1911: 147 per 1000). Mussolini felt that the lack of enthusiasm shown by the Italian nation had cost him 15 army divisions in World War II.
In his self-titled “Speech of the Ascension,” Benito Mussolini, declared that while “[s]tatistics has expanded its jurisdiction over all phenomena of life,” the aim of the National Fascist Party was to “take great care of the future of the race.” By his view, that meant investing the simple aggregate of a population with racial properties, the resurrection of a conscious, singular people. Indeed, Mussolini delivered this speech on the day of the Catholic feast day of the Ascension in 1926. To that end, he announced the fascist demographic policy of increasing the size of the population through an increase in the birth rate.
For the famous Italian statistician Corrado Gini, best known for his statistical formula measuring the wealth distribution within a national population (the ‘Gini coefficient’), and who was undoubtedly the most prominent government statistician of the Italian fascist government between 1926 and 1932, that argument was more than explicit.
In his 1927 essay “The Scientific Basis of Fascism,” Gini contrasted a liberal understanding of society as “an aggregate of individuals” with a “nationalistic theory,” for which society is “a true and distinct organism of a rank superior to that of the individuals who compose it, an organism endowed with a life … and vital interests of its own,” in which welfare policy meant the “coordination of the desires of the current generation with the with the interests of all the future generations which are to constitute the future life of the nation.”
Monday, December 20, 2021
No more hungry ghosts
Am reading Lu Xun's The Real Story of Ah-Q about a village idiot's life that ends as a dead rebel. Lu Xun is a Chinese literary hero for his short membership in the Shanghai Circle of Communist writers in the early 1920s. I remember reading the same story, probably in Hungarian, under the Stalinist regime. That or a similar story set in the Hungarian countryside. Lu Xun makes fun of traditional Chinese civilization. He hates Chinese Opera, with its noisy gongs and choreographed fights. Mao's Cultural Revolution roots may be found in Ah-Q.
A nun said to Ah-Q : "May you die without descendants!" If I die without descendants, Ah-Q said to himself, I'll have no one to offer a bowl of rice at my grave... and then "There are three ways of betraying your parents, of which dying without descendants is the most serious". They become hungry ghosts.
The Chinese were always a most prolific civilization, how is it that today, the Chinese are not marrying and have no children? The Communist government thinks that the cause is Western influence and contra-Mao's Cultural Revolution, has adopted a pro-children traditionalist attitude. If they follow to the very end of this new tendency, Party cadres - the new mandarines - will have two-three wives and concubines, and clan tombs will be visited yearly to feed a steaming bowl of rice to the ancestors. Illustration: The Hungry Ghosts Festival refers to the opening of hell's gate for one month allowing all the ghosts full liberty to make trouble in the human world of existence. After the one-month period, the ghosts return to hell and the gate is shut for another year.
Sunday, December 19, 2021
Horrible Mutations
Ehlers-Danlos Autosomal recessive
Extreme fragility of the skin, other symptoms include blue sclerae and soft, velvety, hyperextensible skin. Marked bruising and open wounds following minor trauma, the excised skin can be torn by hand. Epidemiology: The disease has been diagnosed among in several Ashkenazi Jewish families In one family in which the origin was determined the grand parents were from Belarus Molecular genetics: ADAMTS2 gene (chromosomal locus 5q23) Homozygozity for the same mutation [Q225X] was found in all the Ashkenazi Jewish patients. Wiki says life expectancy is normal. Pic.: The wiki, from Premalatha S, Sarveswari et al.
Fragile X syndrome
94 X linked dominant FMR1 gene (chromosomal locus Xq27) The disorder is caused by the absence of the FMR1 product, almost always as a result of a CGG repeat unit amplification (> 200 repeats), rarely because of a mutation in the gene. Epidemiology: Among the cases of fragile X syndrome in Israel published in 1997 it was apparent that the disorder is relatively frequent among Jews of Tunisian origin. In the 136 pedigrees surveyed at the time, 36 (26.4%) were of Tunisian Jewish origin. In a Tunisian Jewish control group 4 were carriers of the fragile X mutation (3 premutation, one full mutation). Studying the Tunisian Jewish chromosomes with the mutation, there was an unusually high proportion (20%) that completely devoid AGG interruption. The largest of these uninterrupted alleles was found on a unique haplotypes suggesting a founder effect that may be originating from the Island of Djerba. In several screening programs performed among Jews in Israel the incidence of the disorder was found to be 1:3000. The carrier frequency (more 55 repeats) was approximately 1:150.
From the wiki: Fragile X syndrome has traditionally been considered an X-linked recessive condition with variable expressivity and possibly reduced penetrance.[12] However, due to genetic anticipation and X-inactivation in females, the inheritance of Fragile X syndrome does not follow the usual pattern of X-linked dominant inheritance, and some scholars have suggested discontinuing labeling X-linked disorders as dominant or recessive.[40] Females with full FMR1 mutations may have a milder phenotype than males due to variability in X-inactivation.[citation needed]
Before the FMR1 gene was discovered, analysis of pedigrees showed the presence of male carriers who were asymptomatic, with their grandchildren affected by the condition at a higher rate than their siblings suggesting that genetic anticipation was occurring.[13] This tendency for future generations to be affected at a higher frequency became known as the Sherman paradox after its description in 1985.[13][41] Due to this, male children often have a greater degree of symptoms than their mothers.[42]
The explanation for this phenomenon is that male carriers pass on their premutation to all of their daughters, with the length of the FMR1 CGG repeat typically not increasing during meiosis, the cell division that is required to produce sperm.[13][29] Incidentally, males with a full mutation only pass on premutations to their daughters.[29] However, females with a full mutation are able to pass this full mutation on, so theoretically there is a 50% chance that a child will be affected.[29][36] In addition, the length of the CGG repeat frequently does increase during meiosis in female premutation carriers due to instability and so, depending on the length of their premutation, they may pass on a full mutation to their children who will then be affected. Repeat expansion is considered to be a consequence of strand slippage either during DNA replication or DNA repair synthesis.[43]
Samaritan myopathy
Autosomal recessive. In contrast to other congenital myopathies where muscle weakness is progressive or stable the benign Samaritan congenital myopathy is characterized by an ‘‘inverse’’ course of disease. The patients are severely affected at birth and improve progressively being minimally affected at adult stage. Epidemiology and Molecular genetics: RYR1 gene (chromosomal locus 19q13.1) The diaese was reported in one Samaritan family in which the patients were homozygous for c.3263A>G (p.Tyr1088Cys). The Samaritans are an ethno-religious group of 741 people living in Israel and Nablus. Ancestrally, they consider themselves as descendants of the 10 lost tribes that formed the Kingdom of Israel. The Samaritan population has the highest recorded inbreeding coefficient in human populations due to almost exclusive intra-lineage marriages.